Dog Liver Microsomes

Price range: $85.00 through $95.00

Dog liver microsomes are widely used as in vitro tools for drug metabolism and enzyme activity studies.

SKU: dog-liver-microsomes Category:
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Dog liver microsomes are subcellular fractions enriched with intact drug-metabolizing enzymes, including cytochrome P450 (CYP) enzymes, UDP-glucuronosyltransferases (UGTs), and flavin-containing monooxygenases (FMOs). They are essential in vitro tools for studying metabolic stability, drug–drug interactions, toxic metabolite formation, and interspecies differences. MileCell provides high-quality liver microsomes from multiple species, including mouse, rat, dog, monkey, minipig, rabbit, feline, hamster, etc.

Product features
  • Quality assurance: All batches undergo comprehensive quality control procedures to ensure product integrity and batch-to-batch consistency.
  • Comprehensive characterization: Key CYP and phase II enzyme activities are characterized to ensure consistent metabolic performance and specificity.
  • Scalable production: Large lots derived from pooled liver subcellular fractions minimize lot-to-lot variation and support long-term study continuity.
  • Well-stocked inventory: Fresh, high-quality microsomes are readily available.
  • Customizable options: Gender, species, vial size, and batch size available upon request.
Quality
  • Protein concentration: 20 mg/mL
  • Metabolic activity: Characterization of phase I (CYP1A, 3A, 2C, 2D, FMO) and phase II (ECOD, UGT) drug-metabolizing enzymes
  • Metabolic stability: Determine the half-life of testosterone, verapamil, raloxifene