Liver Microsomes
In drug discovery and preclinical drug development, subcellular fractions play a crucial role in assessing species differences, metabolite formation, metabolic stability, intrinsic clearance, enzyme mapping, and inhibition and induction of CYPs and UGTs.
Product Features
  • Monkey
  • Dog
  • Rat
  • Mouse
  • Hamster, Rabbit, Minipig, Human: SOON
Ordering Information

Cat Number

Description

Size

LMSD-100P

Pooled Male SD Rat Liver Microsomes

0.5mL x 20mg/mL

LMWH-100P

Pooled Male Wistar Han Rat Liver Microsomes

0.5mL x 20mg/mL

LMCD-100P

Pooled Male CD-1 Mouse Liver Microsomes

0.5mL x 20mg/mL

LMCB-100P

Pooled Male C57BL/6 Mouse Liver Microsomes

0.5mL x 20mg/mL

LMBD-100P

Pooled Male Beagle Dog Liver Microsomes

0.5mL x 20mg/mL

LMNR-100P

Pooled Male New Zealand Rabbit Liver Microsomes

0.5mL x 20mg/mL

LMCY-100P

Pooled Male Cynomolgus Monkey Liver Microsomes

0.5mL x 20mg/mL

LMRM-100P

Pooled Male Rhesus Monkey Liver Microsomes

0.5mL x 20mg/mL


Customized services are available with a production cycle of 12 weeks



Metabolic stablility in Beagle Dog liver microsomes

Liver Microsomes (图1)

The above pictures depict stability experiments conducted on beagle dog liver microsome products. 


In comparison to liver microsomes from Brand A, the MileCell  Bio Lot #BD-V233 liver microsomes exhibit shorter half-lives (t1/2) for two test compounds. Specifically, BD-V233-1 and BD-V233-2, two randomly selected microsome vials from Lot BD-V233, demonstrated consistent metabolic stability results within the microsomal product batch.