3D Hepatocyte Spheroids for Long-Term Toxicity Models
Long-term hepatotoxicity studies ask a different question from short metabolic incubations: can an in vitro liver model remain sufficiently liver-like while exposure and cellular responses evolve over time? For this type of study design, maintaining hepatocyte viability is only part of the challenge. Researchers also need a culture format that preserves a physiologically relevant phenotype […]
