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Day: September 1, 2026

Plateable Hepatocytes for DILI and Transporter Studies

Plateable Hepatocytes for DILI and Transporter Studies

Drug-induced liver injury (DILI) and hepatic transporter studies often demand more from an in vitro liver model than short-term metabolic turnover. The cells need to attach reliably, maintain hepatocyte morphology, and – for many transporter workflows – recover the polarity and bile canaliculi architecture that are central to hepatobiliary handling.Plateable primary hepatocytesare designed for this […]

When to Use Sandwich-Cultured Hepatocytes

When to Use Sandwich-Cultured Hepatocytes

Sandwich-cultured hepatocytesare most useful when the study question depends on polarized hepatocyte function rather than attachment alone. Plateable hepatocytes can be used in monolayer, sandwich-culture, and spheroid formats, but the sandwich configuration is specifically designed to support re-establishment of cellular polarity and formation of bile canaliculi-like networks. That distinction matters for transporter and hepatobiliary studies. […]