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Primary Rodent Hepatocyte models

2024.05.20

Title: Primary Rodent Hepatocyte models

Subtitle: Milecell Bio Sprague Dawley Rat Hepatocytes for Enhanced In Vitro Screening Models


In vitro hepatocyte models are essential for fundamental research and diverse applications, closely mirroring liver function for studying drug metabolism and toxicity. Rat primary hepatocytes, derived from SD or Wistar Han strains, offer physiological relevance, reducing ethical concerns and costs in experimentation.


Our flagship products, Rat SD and Rat Wistar hepatocytes, exemplify our commitment to liver cell research and drug development. We present the assessment of MC high-quality cryopreserved SD rat hepatocytes for maintaining a sustained monolayer culture over 72 hours.



图片1.png

Figure 1. Qualification of Milecell Bio high-quality cryopreserved sprague dawley rat hepatocytes 

for sustained monolayer culture over 72 hours


These primary hepatocytes are pivotal in creating hepatic 2D sandwich cultures and 3D spheroids, simulating the liver microenvironment for drug metabolism studies and disease modeling, including long-term toxicity assessment.

Primary Rodent Hepatocyte models(图2)


Figure 2: Milecell Bio Spheroid qualified plateable hepatocytes: 

Rat SD hepatocyte spheroids in ultra-low adhesion (ULA) plate


Our products undergo rigorous quality control, ensuring unparalleled reliability and versatility in drug metabolism studies, toxicity screening, and disease modeling. Customized solutions and scientific support further enhance experiment success, while adherence to regulatory standards guarantees product safety.


Comprehensive Excellence: Rat Primary Hepatocytes for Advanced Research

Quality Control: Our rat primary hepatocytes undergo rigorous screening and testing to guarantee unparalleled quality and reliability. We provide large batches of cryopreserved cells with excellent post-thaw viability and attachment performance, making them ideal for various applications, including 2D sandwich cultures and 3D liver spheroid construction


Versatile Applications: Our rat primary hepatocytes excel in drug metabolism studies, toxicity screening, and disease modeling, demonstrating high versatility.


Performance Optimization: Through production optimization processes, our rat primary hepatocytes exhibit outstanding metabolic activity, physiological relevance, and long-term viability, guaranteeing accurate experimental results.


OEM and Customized Production: We provide customized solutions tailored to specific research needs, from cell isolation protocols to specialized culture medium formulations.


Scientific Support: With an experienced team, we offer comprehensive scientific support to ensure experiment success. Milecell rigorously inspects and validates the quality of its mouse primary hepatocytes, ensuring compliance with regulatory standards.


Our premium rat primary hepatocytes stand as the cornerstone of advanced pharmaceutical research, offering unmatched quality, versatility, and scientific support for groundbreaking discoveries in drug development and liver biology.


Summary: Milecell Bio introduces cryopreserved Sprague Dawley rat hepatocytes for advanced in vitro screening models in pharmaceutical research. These high-quality hepatocytes offer unparalleled reliability and versatility, facilitating drug metabolism studies, toxicity screening, and disease modeling. With rigorous quality control, customized solutions, and scientific support, MB ensures experiment success and compliance with regulatory standards, making them the ideal choice for cutting-edge research in liver biology and drug development.


Table 1: Rat SD and Rat Wistar Hepatocyte Product List

Catalog Number

Discription

Size

Suspension Hepatocytes

CRH-100SD-SQ

Cryopreserved Male SD Rat Hepatocytes (Pooled, Suspension & Metabolism Qualified)

5 million/vial

CRH-100WH-SQ

Cryopreserved Male Wistar Han Rat Hepatocytes (Pooled, Suspension & Metabolism Qualified)

5 million/vial

Plateable Hepatocytes

CRH-100SDP-PQ

Cryopreserved Male SD Rat Hepatocytes (Pooled, Plateable Qualified)

5 million/vial

CRH-100WHP-PQ

Cryopreserved Male Wistar Han Rat Hepatocytes (Pooled, Plateable Qualified)

5 million/vial